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The endogenous amide N-Oleoylglycine (OlGly) and its analog N-Oleoylalanine (OlAla), have been shown to interfere with the affective and somatic responses to acute naloxone-precipitated MWD in male rats.Here we evaluated the potential of a single dose (5 mg/kg, ip) which alleviates withdrawal of these endogenous fatty acid amides to modify tolerance to anti-nociception, hyperthermia, and.
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Electron Micrograph
OlGly and OlAla suppress EtOH self-administration and preference. We have previously shown that OlGly was elevated in a region-speci c manner in the NAc of male mice chronically treated with fi.
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Rationale The fatty acid amide oleoyl glycine (OlGly) and its more stable methylated form oleoyl alanine (OlAla) reduce naloxone-precipitated morphine withdrawal (MWD)-induced conditioned gaping (nausea) responses in rats. In addition, OlGly has been shown to reduce lithium chloride (LiCl)-induced conditioned gaping in rats and vomiting in Suncus murinus (house musk shrews). Objectives Here.
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Highlights Aldosterone is the major mineralocorticoid produced by the adrenal zona glomerulosa. Glomerulosa cells are primarily regulated by angiotensin II, serum potassium and ACTH. Aldosterone synthesis involves two key phases, acute and chronic. Cholesterol delivery into mitochondria is the rate-limiting step in the acute phase. Aldosterone synthase (CYP11B2) is the rate-limiting step in.
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Coelution of OlAla with an isobaric compound (shown separated in Figure 2 with the presented mobile phase gradient) occurred when the starting mobile phase was 60% mobile phase B which did not allow an isobaric compound of OlAla to chromatographically resolve. Using the presented method allowed for the separation of potential interferences from isobaric compounds found in the brain tissue samples.
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The endogenous amide N-Oleoylglycine (OlGly) and its analog N-Oleoylalanine (OlAla), have been shown to interfere with the affective and somatic responses to acute naloxone-precipitated MWD in male rats. Here we evaluated the potential of a single dose (5 mg/kg, ip) which alleviates withdrawal of these endogenous fatty acid amides to modify tolerance to anti-nociception, hyperthermia, and.
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Mol Cell Endocrinol. 2012 Mar 24;350(2):151-62. doi: 10.1016/j.mce.2011.07.034. Epub 2011 Aug 4. Authors Namita G Hattangady 1 , Lawrence O Olala, Wendy B Bollag, William E Rainey. Affiliation 1 Department of Physiology, Georgia Health Sciences University (formerly Medical College of Georgia), 1120 15th Street, Augusta, GA 30912, USA..
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Freely permeable layer surrounding cell membrane. The cell wall of plant cells is made from cellulose. This gives them a rigid structure. Supports and strengthens cell. Plant cell, fungal cell or.